Panjab University Researchers Develop Eco-Friendly Nanomicelle Platform; File Indian and International Patent Applications

In a significant stride toward sustainable pharmaceutical innovation, researchers from Panjab University have developed a pioneering green nanomicelle platform that promises to revolutionize drug delivery systems. The invention, which is both solvent-free and environmentally friendly, has led the university to file patent applications in India and internationally, highlighting the platform’s global potential and scientific merit.

The innovation is the result of dedicated research led by Professor Indu Pal Kaur from the University Institute of Pharmaceutical Sciences, along with her PhD scholars Bakr Ahmed and Simrandeep Kaur. Together, the team has designed a scalable nanomicelle-based system that addresses critical challenges in the pharmaceutical industry, including eco-sustainability, biocompatibility, and cost-effectiveness.

Nanomicelles are tiny, spherical structures formed by the self-assembly of amphiphilic molecules, widely used for enhancing the solubility and targeted delivery of poorly water-soluble drugs. However, traditional methods of creating these nanocarriers often rely on toxic organic solvents and energy-intensive processes, raising concerns about environmental impact and safety.

What sets this new platform apart is its green synthesis approach — completely free from harmful solvents, making it safer for both patients and the environment. The process is not only non-toxic but also easily reproducible on a large scale, offering significant potential for industrial adoption.

“The development of this green nanomicelle platform stems from our commitment to merging scientific excellence with environmental responsibility,” said Prof. Indu Pal Kaur. “Our system is highly adaptable, stable, and can encapsulate a wide range of drug molecules, especially those that are poorly soluble in water, improving their bioavailability and therapeutic efficiency.”

Preliminary studies have demonstrated the nanomicelles’ stability, high encapsulation efficiency, and sustained drug release capabilities. These features make the platform suitable for various medical applications, particularly in oncology, infectious diseases, and chronic illness management, where precision and prolonged drug action are critical.

Recognizing the global relevance of the technology, Panjab University has moved swiftly to protect the intellectual property by filing for both Indian and Patent Cooperation Treaty (PCT) international patents. This strategic move ensures the platform’s commercial potential can be leveraged not only in India but across global markets.

“The green nanomicelle platform reflects the university’s vision of fostering innovation that aligns with sustainable development goals,” said a spokesperson from Panjab University’s Innovation and Entrepreneurship Development Centre. “It’s a proud moment that exemplifies how cutting-edge research can contribute to both healthcare advancement and ecological balance.”

The university is now exploring partnerships with pharmaceutical companies for technology transfer, aiming to bring this innovation from the lab to the marketplace. The research team is also working on further pre-clinical validation and is hopeful about future collaborations for clinical translation.

As the global pharmaceutical sector increasingly shifts focus toward green technologies, Panjab University’s contribution through this solvent-free nanocarrier platform is both timely and transformative. It sets a new benchmark in combining scientific ingenuity with sustainable practices, reinforcing India’s role as a leader in eco-conscious health innovation.

Clearmind Medicine Secures European Patent Publication for Psychedelic-Based Cocaine Addiction Therapy

Clearmind Medicine Inc. (Nasdaq: CMND, FSE: CWY0), a clinical-stage biotechnology firm focused on the development of next-generation psychedelic-based treatments, has officially announced the publication of a European patent application for its novel cocaine addiction therapy. The patent, filed with the European Patent Office (EPO) under number EP 4531826, represents a critical milestone in the company’s mission to address substance use disorders with innovative, non-addictive therapeutic solutions.

A Groundbreaking Therapeutic Combination

The newly published patent centers around a proprietary formulation that combines MEAI (5-methoxy-2-aminoindane) with N-Acylethanolamines (NAEs), including Palmitoylethanolamide (PEA). This unique combination aims to reduce cocaine cravings and prevent relapse by targeting the neurological pathways associated with drug addiction, without negatively impacting the natural reward systems in the brain.

These studies showed that animals treated with MEAI experienced a significant reduction in drug-seeking behavior. Notably, the research also found that the treatment did not impair the animals’ motivation for natural rewards such as sucrose, indicating the therapy’s ability to specifically address compulsive drug use without affecting healthy reward mechanisms.

Enhancing Global IP Protection

The European patent publication marks a key development in Clearmind’s broader strategy to strengthen its global intellectual property portfolio. The company has filed similar patent applications in multiple jurisdictions, and this European recognition further validates its proprietary approach to addiction therapy.

“This milestone reinforces our commitment to protecting the science behind our innovative treatments,” said Adi Zuloff-Shani, Ph.D., CEO of Clearmind Medicine. “Securing intellectual property rights in major global markets is essential for supporting the future commercialization of our psychedelic-based therapeutics and ensuring continued leadership in this evolving field.”

Strategic Collaboration and Expansion

The patent is also part of an ongoing collaborative effort with SciSparc Ltd. (Nasdaq: SPRC). The partnership is exploring the combined potential of Clearmind’s MEAI compound with SciSparc’s PEA-based technologies to develop advanced treatments for a range of central nervous system (CNS) disorders. This alliance is expected to further accelerate the development of therapies targeting addiction, anxiety, depression, and other mental health conditions.

About Clearmind Medicine Inc.

Clearmind Medicine is a clinical-stage psychedelic pharmaceutical company dedicated to creating transformative solutions for pressing and under-treated health conditions. Its research and development efforts focus primarily on psychedelic-derived compounds, with the goal of advancing them through the regulatory pipeline for use as pharmaceutical treatments, functional supplements, or food-grade therapies.

The company currently manages an expansive IP portfolio comprising 19 patent families and 31 granted patents, and continues to pursue additional filings to protect its proprietary formulations and discoveries.


The publication of this European patent application represents a significant leap forward in Clearmind’s pursuit of effective therapies for cocaine addiction. By combining rigorous scientific research with strategic global partnerships and IP protection, the company continues to establish itself as a leader in the emerging field of psychedelic-based mental health treatments.