ABVC BioPharma Secures Japanese Patent for Botanical Depression Drug ABV-1504, Strengthens Global IP Portfolio

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In a significant boost to its intellectual property portfolio, U.S.-based clinical-stage biopharmaceutical company ABVC BioPharma has received a key patent grant in Japan for its novel antidepressant candidate, ABV-1504. The newly issued patent secures exclusive rights in Japan for the innovative botanical-based treatment through 2040, reinforcing the company’s commitment to addressing global mental health challenges with plant-derived therapies.

ABV-1504, currently under clinical development for Major Depressive Disorder (MDD), is formulated from PDC-1421, a proprietary compound extracted from the traditional medicinal herb Polygala tenuifolia. This active ingredient acts as a Norepinephrine Transporter (NET) inhibitor and has shown encouraging safety and efficacy in Phase II clinical trials, offering a potentially safer and non-addictive alternative to conventional treatments like selective serotonin reuptake inhibitors (SSRIs).

The Japanese patent adds to ABVC’s existing IP protections in the United States, Australia, and Taiwan, ensuring broad international coverage for PDC-1421. With depression affecting more than 280 million people globally, and the antidepressant market projected to reach $20 billion by 2030, ABV-1504 positions itself as a differentiated and promising therapy in a growing global landscape.

“Securing patent protection in Japan is a critical achievement for ABV-1504 and reflects our broader strategy to provide innovative, plant-based solutions for central nervous system disorders,” said a company representative. “Japan’s healthcare system, which has long embraced botanical therapies, represents an ideal market for introducing this novel treatment.”

Japan presents strong commercial potential for ABV-1504. With over 5 million people suffering from depression and the country’s antidepressant market expected to surpass $1.25 billion by 2025, ABVC sees the region as a vital part of its global expansion strategy. The integration of herbal medicine into Japan’s modern healthcare practices further enhances market readiness for scientifically validated botanical alternatives.

To accelerate market access and local engagement, ABVC established BioLite Japan K.K., a joint venture led by a former Pfizer executive with deep experience in the Asia-Pacific pharmaceutical industry. Through this entity, ABVC is actively collaborating with regulatory bodies, academic institutions, and local industry leaders to prepare for future clinical and commercial developments in the region.

In a parallel development, ABVC signed a global licensing deal in November 2023 with AiBtl BioPharma Inc., valued at $667 million. The agreement includes milestone payments and royalties based on future commercialization success, underscoring investor confidence in the compound’s potential.

The issuance of the Japanese patent represents a major milestone for ABVC BioPharma as it continues its mission to redefine the treatment landscape for mental health disorders. By advancing a botanical-based solution with proven clinical promise, ABVC aims to offer patients a new path toward safer and more sustainable depression management.

China Strengthens IP Protection with New Fast-Track Service Center in Shenzhen’s Futian District

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In a significant move to bolster the nation’s innovation ecosystem, China has approved the establishment of a new national-level fast-track intellectual property rights (IPR) protection service center in Shenzhen’s Futian district. The announcement was made by the China National Intellectual Property Administration (CNIPA), marking another milestone in the country’s expanding IP protection infrastructure.

Futian, located in the core of Shenzhen’s central business area, is widely recognized for its vibrant fashion industry. The new IPR center is expected to provide significant support to these businesses by offering streamlined services for securing design patents.

According to CNIPA, the new facility will be focused on expediting the design patent application process. Typically, it takes around six months for a design patent to be approved in China. However, with the assistance of the new service center, this duration can be reduced to within three months, enabling companies to protect their innovations more quickly and effectively.

“Fast-track services like those offered by the Futian center are essential for industries where product design changes rapidly and time-to-market is critical,” said a CNIPA spokesperson. “By accelerating the IP protection process, we aim to enhance innovation capabilities and create a more favorable environment for creative industries.”

Design patents represent a substantial portion of China’s intellectual property filings. In 2023 alone, China granted 638,000 design patents, and in 2024, the country maintained its position as the global leader in international design patent filings. The introduction of fast-track services in innovation-driven zones like Futian is seen as a strategic step toward sustaining this momentum.

The center will also contribute to the local economy by attracting more fashion designers and creative talent to the district. Small and medium-sized enterprises (SMEs), in particular, are expected to benefit, as they often face resource constraints when navigating traditional IP processes. By offering efficient services, the new center aims to reduce barriers for these businesses and empower them to compete on a larger scale.

This initiative is part of a broader national effort to create a comprehensive IP protection

Catheter Precision Secures First U.S. Patent for Surgical Closure Device, LockeT

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Catheter Precision, Inc. (NYSE American: VTAK), a leading U.S.-based developer of advanced medical devices in the cardiac electrophysiology field, has received a significant boost to its intellectual property portfolio. The company announced today that the United States Patent and Trademark Office has issued a notice of allowance for its first U.S. patent for LockeT, a specialized surgical closure device designed for orthoscopic entry wounds. The patent application was originally filed in December 2022.

LockeT, a Class 1 device registered with the U.S. Food and Drug Administration (FDA), is a suture retention product aimed at facilitating wound closure following percutaneous venous procedures. This latest patent strengthens Catheter Precision’s competitive position in the U.S. market and builds upon its growing foundation of international intellectual property protections.

“This first U.S. patent for LockeT complements our portfolio of international patents already granted in China, Europe, and the United Kingdom,” said David Jenkins, Chief Executive Officer of Catheter Precision. “Securing IP protection in the U.S. is particularly meaningful as we continue discussions for product distribution in key global markets, including China and Europe.”

The company is also anticipating regulatory clearance in the form of a CE mark within the current quarter, which would authorize LockeT’s commercial use across European markets. According to Jenkins, this approval is expected to open new revenue opportunities and accelerate market entry efforts abroad.

“We’re encouraged by the reception LockeT has received since its limited rollout in the U.S. late last year,” Jenkins added. “Healthcare systems globally are increasingly looking for devices that can improve clinical outcomes while also reducing overall procedural costs. LockeT is well-positioned to meet these dual objectives.”

LockeT represents a key addition to the company’s product lineup, especially as hospitals and surgical centers seek more effective wound management solutions that minimize complications and enhance recovery.

About Catheter Precision
Based in the United States, Catheter Precision, Inc. is a medical technology company dedicated to improving the treatment of cardiac arrhythmias. The company collaborates closely with clinicians to design and deliver innovative electrophysiology devices that raise the standard of care in cardiac procedures.

Forward-Looking Information
This news article contains statements that may be considered forward-looking under the Private Securities Litigation Reform Act of 1995. Such statements involve risks and uncertainties, including those related to product approvals, market adoption, and commercial success. Actual results may differ materially due to various factors, including those detailed in the company’s filings with the Securities and Exchange Commission (SEC).

Conduit Pharmaceuticals Receives Additional Patent Approval for Lead Autoimmune Disease Asset

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Conduit Pharmaceuticals Inc. (NASDAQ: CDT), a biopharmaceutical company focused on developing treatments for autoimmune and inflammatory diseases, announced today that it has received further patent approval for its lead therapeutic asset targeting autoimmune conditions. The newly granted patent strengthens the company’s intellectual property portfolio and provides added protection for its innovative approach to treating autoimmune diseases such as sarcoidosis and lupus.

The patent, issued by the United States Patent and Trademark Office (USPTO), covers key methods of use and compositions relating to Conduit’s investigational drug, which is designed to modulate the immune response in patients with chronic autoimmune disorders. According to company officials, the approval not only broadens the existing patent family but also enhances the commercial potential of the lead compound as it advances through clinical development.

“This new patent grant is a major milestone for Conduit Pharmaceuticals, as it secures crucial proprietary rights over our lead autoimmune asset,” said Dr. David Tapolczay, Chief Executive Officer of Conduit Pharmaceuticals. “Our mission is to bring safe and effective treatments to patients suffering from complex autoimmune conditions, and this patent approval is a significant step forward in protecting the innovation that underpins our approach.”

The company’s lead asset, originally acquired from a major pharmaceutical partner, has demonstrated promising results in preclinical and early clinical studies. The drug works by selectively targeting pathways involved in the overactive immune response characteristic of autoimmune diseases, while minimizing systemic immunosuppression.

Conduit Pharmaceuticals has emphasized its strategy of revitalizing underutilized assets from larger pharmaceutical companies and accelerating them through late-stage development. The expanded patent protection ensures a longer runway for exclusivity, which could facilitate future licensing agreements or commercial partnerships.

Industry analysts view the patent approval as a positive development that enhances Conduit’s valuation and strengthens its position in the competitive autoimmune drug market, projected to surpass $150 billion globally by 2030.

The company plans to continue progressing its lead candidate through clinical trials, with additional updates expected later this year regarding regulatory filings and potential Phase 2 study initiations.

For more information, visit www.conduitpharma.com.

WHO and Medicines Patent Pool Support Nigerian Innovation in Health Diagnostic

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In a landmark step towards strengthening healthcare innovation in Africa, the World Health Organization (WHO) and the Medicines Patent Pool (MPP) have announced strategic support for Nigerian-led advancements in health diagnostics. This collaboration is aimed at fostering local innovation, improving access to affordable diagnostic tools, and enhancing the country’s capacity to respond to pressing public health challenges.

The initiative comes under WHO’s Global Initiative on Digital Health and the MPP’s commitment to equitable access to medical innovations. Nigeria has been identified as a critical partner due to its growing innovation ecosystem and urgent need for scalable, cost-effective diagnostic solutions for diseases such as malaria, tuberculosis, hepatitis, and HIV/AIDS.

Speaking at a press briefing in Abuja, WHO Nigeria Country Representative, Dr. Walter Kazadi Mulombo, emphasized the importance of locally developed technologies in transforming health outcomes. “Nigeria has demonstrated significant potential in biomedical innovation,” he stated. “By supporting homegrown diagnostic solutions, we aim to empower Nigerian researchers and entrepreneurs to develop tools that are not only technologically sound but also contextually appropriate for local health challenges.”

The partnership will provide technical assistance, funding opportunities, and pathways to intellectual property management through the MPP. Nigerian innovators will gain access to international patent licensing frameworks, regulatory support, and opportunities for technology transfer. This is expected to facilitate the development, manufacturing, and distribution of diagnostics that meet global standards while remaining affordable for local healthcare systems.

“Affordable diagnostics are a cornerstone of universal health coverage,” he said. “Through this collaboration, we aim to bridge the gap between innovation and access, ensuring that promising technologies from Nigeria can benefit both the country and the wider global South.”

Among the early beneficiaries of the initiative is a Lagos-based biotech startup that has developed a rapid point-of-care diagnostic test for tuberculosis, which uses AI-powered image recognition. Another group from Ahmadu Bello University is working on a low-cost paper-based testing kit for hepatitis B and C, tailored for use in rural and underserved communities.

Health experts have welcomed the announcement, noting that empowering local solutions can reduce dependency on imported diagnostics and improve response times during outbreaks. Dr. Amina Balogun, a public health analyst, noted: “This kind of support is crucial for building a self-reliant health system. It’s not just about the tools, but about building confidence and capacity in our institutions and scientists.”

As part of the next phase, WHO and MPP plan to host a regional innovation forum in Nigeria later this year to showcase emerging diagnostic technologies and connect local developers with global health agencies and funders.

This partnership marks a significant step in aligning Nigeria’s innovation capacity with global health goals and demonstrates how strategic international collaboration can empower local solutions to meet both national and international health needs.

Agfa Loses Patent Dispute Against Gucci Over Leather Decoration Method

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Printing technology company Agfa has filed a patent infringement lawsuit against luxury fashion house Gucci, alleging unauthorized use of its patented method for decorating natural leather. The legal battle centered on Agfa’s European patent EP 3 388 490, which covers a process for embellishing leather surfaces with decorative images—a technique the company considers vital to its future innovation strategy.

The dispute specifically involved Gucci’s Pikarar Collection, which Agfa claimed employed its patented method without authorization. However, the Local Division of the Unified Patent Court (UPC) in Hamburg dismissed both Agfa’s infringement claim and Gucci’s counterclaim for patent invalidation (Case ID: ACT_561734/2023).

Presiding Judge Sabine Klepsch and her panel deemed both the infringement action and the revocation counterclaim admissible, but ultimately ruled against both parties. The court’s decision was based on a detailed analysis of the patent language, drawing on precedent established in earlier UPC rulings, such as the NanoString vs. 10x Genomics case. The court concluded that the interpretation of certain terms in the patent should differ from their conventional meanings, resulting in a finding of no infringement on Gucci’s part.

This case marks the first time a luxury fashion brand has been involved in litigation before the newly established Unified Patent Court. The ruling offers some relief to the fashion industry, although Agfa still has the option to appeal.

Agfa was represented by a legal team jointly led by Daan de Lange of the Netherlands and Kai Rüting of Germany. The case also marked the first major matter handled by Vossius Brinkhof UPC Litigators, a new collaboration between Dutch and German law firms. Other members of the legal team included Stefan Fickert, Ananda Landwehr, Leonie Dissmann-Fuchs, Elard Schenck zu Schweinsberg, Isabelle Kleinveld, and Alexander de Leeuw. Hans Louis Strijckers managed the case internally for Agfa.

Although the decision did not go in Agfa’s favor, the company’s aggressive defense of its patent portfolio signals its strategic focus on emerging technologies in leather decoration.

AI Tools Accelerate Insights in CAR T-Cell Therapy Research for Multiple Myeloma

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A research team focused on advancing chimeric antigen receptor (CAR) T-cell therapies has harnessed artificial intelligence tools to streamline data analysis and extract key insights in the field. Their work was highlighted as part of the late-breaking research presented at the 2025 American Association for Cancer Research (AACR) Annual Meeting in Chicago, Illinois.

The investigators explored the evolving landscape of CAR T-cell treatments for multiple myeloma (MM) by leveraging two AI-powered platforms: BiblioEngine, developed by 23Strands, and Cool.AF from Neural Hinge. These tools were used to mine publicly accessible clinical literature, with a focus on manufacturing methods, clinical trial structures, and therapeutic outcomes. The team also conducted a comprehensive review of related patent filings across jurisdictions including the United States, European Union, and India.

By utilizing AI-driven analytics, the researchers efficiently processed large volumes of data and identified emerging trends in how CAR T-cell therapies are developed and applied in real-world clinical settings. The tools enabled detailed comparisons between datasets, shedding light on factors influencing successful patent applications and highlighting the structure of collaborative networks among researchers in the field.

The analysis not only revealed current gaps in MM treatment strategies but also pointed to opportunities for future innovation and patent development. These findings are expected to guide more strategic clinical trial design and support intellectual property planning that avoids overlap with existing patents.

Moreover, the team’s work identified opportunities to foster new research partnerships by mapping the relationships among authors in the field, potentially expanding the collaborative network and accelerating progress in CAR T-cell therapy innovation.

Heron Therapeutics Reaches Patent Settlement with Mylan Over Cancer-Related Drugs

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Heron Therapeutics, Inc. (NASDAQ: HRTX), a commercial-stage biopharmaceutical firm valued at approximately $324 million, has resolved ongoing patent litigation with Mylan Pharmaceuticals, Inc., a Viatris Inc. subsidiary.

Under the terms of the agreement, Heron has granted Mylan the right to begin selling generic alternatives to both drugs starting June 1, 2032. This resolution ends two separate legal proceedings filed in the U.S. District Court for the District of Delaware, which were initiated in September 2023 and January 2024 after Mylan sought FDA approval for generics ahead of the drugs’ patent expirations in 2035. As part of the agreement, both companies will ask the court to dismiss the lawsuits.

CINVANTI® and APONVIE® are formulations of the active ingredient aprepitant, used to prevent chemotherapy-induced nausea and vomiting. The deal allows for the possibility of an earlier launch of Mylan’s generics under standard conditions, although the formal market entry date remains set for 2032.

Heron, known for its focus on acute care and oncology-related treatments, continues to show signs of financial health and strategic growth. InvestingPro data shows a solid current ratio of 2.29, indicating strong short-term liquidity. The company has also reported a 13.57% increase in revenue over the last 12 months.

The patent settlement comes on the heels of a strong fourth quarter for Heron. The company reported adjusted earnings of $0.02 per share, outperforming analysts’ expectations of a $0.03 loss. Quarterly revenue reached $40.78 million—above the $37.3 million forecast—and reflected a 19.1% increase year-over-year. A significant contributor was ZYNRELEF, Heron’s pain management therapy, which brought in $8.5 million in Q4, up nearly 49% from the same period last year.

For the full year 2024, Heron posted total revenue of $144.2 million, a 13.6% increase compared to 2023. Looking ahead, the company projects 2025 revenues between $153 million and $163 million, in line with analyst expectations. Additionally, Heron estimates adjusted EBITDA between $0 and $8 million for the year.

In December 2024, the company expanded the label indications for ZYNRELEF and introduced a new vial access needle, further enhancing its product offerings. Heron closed the year with $59.3 million in cash and short-term investments, reinforcing its financial stability as it continues to grow its commercial footprint.

Baidu Explores AI Technology to Decode Animal Communication

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Ever wondered what your cat’s meows actually mean? Chinese tech giant Baidu is aiming to bridge the communication gap between humans and animals with the help of artificial intelligence.

The proposed technology would combine data on animal vocalizations, behavioral cues, and bodily responses, then process this information using AI to identify emotional states. These emotional indicators would subsequently be translated into semantic content understandable by humans.

Baidu’s patent describes the project as a step toward “deeper emotional communication and understanding between animals and humans,” potentially making cross-species interaction more accurate and efficient. While the concept has captured public interest, the company has clarified that the system remains in the research phase.
This effort is part of Baidu’s broader strategy to lead in AI innovation. The company has been investing heavily in artificial intelligence since the rise of OpenAI’s ChatGPT in 2022. Baidu recently introduced its advanced AI model, Ernie 4.5 Turbo, claiming it performs at the top tier across industry benchmarks. Despite these advancements, Baidu’s chatbot offerings have faced challenges in gaining widespread user adoption due to intense competition.

Globally, Baidu is not alone in its quest to decode animal language. Projects like CETI (Cetacean Translation Initiative), launched in 2020, are working to interpret the complex communication of sperm whales using AI and statistical models. Meanwhile, the Earth Species Project, founded in 2017 and backed by tech figures like LinkedIn co-founder Reid Hoffman, is also using artificial intelligence to analyze animal communication across various species.

While the dream of talking to animals like a real-life Dr. Dolittle remains a long-term goal, advances like Baidu’s patent hint at a future where technology could help us better understand the emotional and communicative world of animals.

DCRUST Researcher Secures Patent for Energy-Efficient Clay Cooler

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Mukesh Kumar, a research scholar from the Mechanical Engineering Department at Deenbandhu Chhotu Ram University of Science and Technology (DCRUST), Murthal, has developed an innovative clay-based cooler that uses only half the electricity of conventional air coolers. This eco-friendly invention has now been granted a patent by the Central Government’s Patent Office.

The energy-efficient cooler was developed under the guidance of Prof. Amit Sharma, Associate Professor in the same department. The project was recently recognized at the university, where Vice-Chancellor Prof. Prakash Singh honored both Mukesh Kumar and Prof. Sharma for their contribution to sustainable technology.

Prof. Singh highlighted the importance of research in enhancing the academic standing of universities and praised the clay cooler as an initiative aligned with the United Nations’ Sustainable Development Goals, especially those focusing on affordable and clean energy solutions.

This innovation not only represents a step forward in green technology but also holds socio-economic promise. By involving traditional potter communities in the production process, it can potentially improve their livelihoods and create new employment opportunities. The biodegradable nature of the cooler ensures it leaves no harmful residue, contributing positively to environmental sustainability.

Describing the project as a blend of innovation and environmental responsibility, Prof. Sharma said the cooler utilizes the natural cooling properties of soil to deliver efficiency and eco-friendliness. He also emphasized its potential to support the government’s Make in India campaign by fostering domestic innovation and production.

The development of the cooler involved extensive testing and experimentation. Mukesh Kumar collected soil samples from various states. After rigorous trials, soil from Sohna, Haryana, was selected as the most suitable material. Despite facing over a hundred failed attempts, Kumar’s persistence paid off with a working model that is both practical and environmentally conscious.

This breakthrough demonstrates how traditional materials, combined with modern engineering, can lead to sustainable solutions with real-world impact.